Prague is not only an amazing historical city with a wealth of monuments, excellent gastronomy, cordial residents, and a wide range of events. It is also a modern and innovative science hub. Prague excels in many fields, such as artificial intelligence and robotics, biomedicine, low-carbon technologies, data technologies and selected creative industries, providing ideal opportunities for holding conventions and conferences with the matching topics.
In the 35th edition of Innovative Prague we will take a look at new technological innovations that are changing the view of the world and modern computer technology. We will explore how scientists in Prague help improve human eyesight or prevent cancer metastases. We must not forget the news in the field of artificial intelligence this time either. We will introduce you to models that make flood forecasting more accurate, analyse geospatial data or examine the condition of airport runways.
Prague’s technological innovations are changing the way we look at the world
And that literally. Scientists from the Institute of Plasma Physics of the Czech Academy of Sciences in cooperation with the Faculty of Nuclear Sciences and Physical Engineering of the Czech Technical University in Prague have developed a unique FASXCAM camera that can monitor X-rays generated in extremely hot plasmas. A camera that can endure high radiation will help researchers control the conditions needed for future nuclear fusion energy production better.
Scientists awarded with the prestigious ACS Nano Impact Award 2026, including Vladislav Pokorný, a physicist from the Institute of Physics of the Czech Academy of Sciences, who is a co-author of the study, showed how much computer memory can be spatially reduced. In the study, scientists have demonstrated the possibility of assembling a miniature memory from molecules on the surface of a superconductor. Another breakthrough in computer technology was then carried out by researchers from the Faculty of Electrical Engineering of the Czech Technical University in Prague and the University of Chemistry and Technology in Prague, who developed a process using waste plastic from the production of gramophone records for the production of printed circuit boards using 3D printing. However, wireless technology did not go unnoticed by scientists. An international team with Czech physicists from the Institute of Physics of the Academy of Sciences has developed a material that can make these electronics consume less energy.
Czech scientists making progress in medical research again
When speaking of observing the world, we should not forget the progress in medicine – specifically in the study of human vision. The study, in which experts from the Czech ELI Centre also participated, brings new knowledge about human vision and possible stimuli for research into eye diseases. For the first time, scientists have succeeded in determining the three-dimensional molecular structure of human cone opsins that allow us to perceive the world around us in daylight. A research team from the Institute of Molecular Genetics of the Czech Academy of Sciences then succeeded in repairing a faulty gene in a genetic disease of the retina that leads to vision loss using modified RNA molecules. However, human vision is not the only field where breakthroughs have been made. An international team of scientists, led by a Czech doctor from Charles University and the University Hospital Královské Vinohrady, Pavla Tichá, has discovered one of the principles that allows tumour cells to evade the immune system and form metastases. This discovery thus opens up possibilities for further development of targeted anticancer treatment.
Prague welcomes new AI projects
New discoveries and technologies will be worked on in Prague not only at existing scientific workplaces, but also at newly established start-ups. One such is PangeAI, which is used to analyse geospatial data, thanks to which it is possible to determine where, for example, to launch new construction development, protect nature more effectively, or where there is a threat of climate risks. The start-up was founded at Stanford, but thanks to co-founder Marek Miltner, it will have a base in Prague. Another important step towards possible implementation was also the project of one of the 7 large AI Gigafactory data centres for artificial intelligence, which should be located in the Czech Republic. The government recently approved support for the Czech Republic’s participation in the European competition for the construction of infrastructure for this centre.
Given that a large number of diverse projects, start-ups and innovations are being created in Prague and throughout the Czech Republic, it can sometimes be difficult to map their existence and current activities. That is why, under the baton of the CzechInvest (newly CzechBusiness) agency, the Czechia Dealroom platform was created, which solves this problem and offers a single place where the involved start-ups, technology companies or research institutions can be seen and where they can be easily found by investors, corporations and foreign partners.
However, not only brand new projects are being created in Prague, cooperation within existing partnerships continues to expand and new ones are being established. One such example is the cooperation between the Czech Technical University in Prague and CISCO, which will explore new approaches to agentic artificial intelligence in Prague with the aim of creating a new generation of AI. Another important international cooperation has resulted in a newly introduced AI model for flood forecasting, in which the Czech Hydrometeorological Institute also participated. Thanks to the new model, flood forecasting will be more accurate and timely, allowing better preparation for floods and reducing their impacts. International cooperation also resulted in recent testing, when the Canadian company Niricson from the Czech cohort of NATO DIANA 2026 demonstrated at the Přerov-Bochor airport, operated by the state-owned company LOM PRAHA, how artificial intelligence and new sensors make the assessment of runway condition faster and more accurate.
These innovations may consider Prague their home, but some projects from Prague go beyond the borders of the Czech Republic, such as the Czech receptionist BE-A of the Prague company Flae Robotics. It can solve up to 85% of their routine requirements with accommodated guests. It currently operates not only in the Czech Republic, but also in the United Kingdom, and the system is planned to expand to neighbouring Germany and Austria in the near future.
Would you like to learn more interesting facts on innovation? Browse through the previous three issues of Innovative Prague: